CO-LUMINATE
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    • Objective 1: Youth Co-Creation
    • Objective 2: Depression Harmonization
    • Objective 3: Social Determinant Trajectories
    • Objective 4: Behavioral Mediators
    • Objective 5: Causal Mediation
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CO-LUMINATE: Co-Creating Knowledge On The Longitudinal Direct And Mediation Relationships Between Youth Mental Health And Social Stress Exposures

Youth Mental Health and Social Stress Exposures

CO-LUMINATE

Co-Creating Knowledge On The Longitudinal Direct And Mediation Relationships Between Youth Mental Health And Social Stress Exposures

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CO-LUMINATE investigates how childhood and adolescent social stress exposures shape depression risk over time among South African youth aged 13-24, using a longitudinally linked dataset nested within the AHRI Health and Demographic Surveillance System (HDSS). The study integrates four connected analytical components: depression endpoint harmonization, social determinant trajectory modeling, behavioral mediator assessment, and causal mediation analysis, with Youth Co-Creators guiding interpretation and context-sensitive framing so that findings remain scientifically rigorous, locally grounded, and policy-relevant.

Study Snapshot

5,279

Young people in linked sample

13-24

Age range

5 Cohorts

Nested within AHRI HDSS

11 YCC

Youth Co-Creators providing thought leadership

Project Overview

CO-LUMINATE leverages the Africa Health Research Institute (AHRI) Health and Demographic Surveillance System (HDSS) to create a longitudinal linked dataset of 5,279 adolescents and young people. The dataset supports analysis of how social determinants of mental health, including socioeconomic status (SES) and caregiver co-residency, relate to depressive symptoms over time.

The project also uses a structured co-creation model with 11 Youth Co-Creators (YCC), who contribute meaningful thought leadership to refine, guide, and nuance the research process and interpretation.

Study Design

1

Longitudinal Linkage

Individual-level depression outcomes are linked to household HDSS trajectories to assess direct and mediation relationships through time.

2

Youth Co-Creation

Eleven YCC members provide co-created input to strengthen relevance, interpretation, and context-sensitive framing of findings, and to guide analytical pathways.

3

Secondary Data Analysis

Longitudinal analyses evaluate relationships between social stress exposures (including SES and caregiver co-residency) and symptoms of depression.

About | Team

 

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